Coffee is one of the most popular drinks in the world with coffee production increasing every year. The post-harvest process of coffee is very susceptible to attack by the fungus Okratoxin A (OTA) which can cause health problems. The purpose of this study was to analyze coffee drinking habits, age and village location on proteinuria content in coffee farmers in BPR Ranau Tengah District OKUS Regency. This type of research is cross sectional with a sample of 304 respondents taken by the proportional stratified random sampling method. Collecting data using questionnaires and observations as well as taking samples of coffee grounds and urine samples of farmers. The data were analyzed using the Chi-Square test and samples of coffee grounds were examined at the MIPA UNSRI Laboratory while the urine samples of farmers were examined at the Laboratory of Doctor Maulana AK Baturaja Hospital. The results showed that there was a significant association between coffee drinking habits and age with proteinuria content with ap value of 0.000, while there was no significant association between location and proteinuria with ap value of 0.179. The results of the examination of coffee grounds showed indications of contamination with OTA with the growth of the fungus Aspergillus section nigri and Aspergillus ochraceus as much as 107 (35.2%).